Any frequent flyer will tell you that is very easy to catch something at 30,000 feet. For one thing folks are very close and secondly the air is drying.
On an Aer Lingus flight from Dublin to London, my seat mate coughed and sneezed his way to LHR. I tried to avoid germs, but it didn't work and I caught a bad cold. It is not expensive to be treated, but if not a member of the EU you have to work at it. In a week I was well and just inconvenienced, but I would have rather stayed well.
This is not surefire, but over thousands of miles we have learned to carry Wet Ones wipes and before touching anything in our seating area to clean the tray, the armrest and the backseat pocket. If there is a video screen get that too. Before boarding we put a small amount of Neosporin in our nostrils. Triple antibiotic also works - this keeps your nose moist and kills germs. Also do drink plenty of liquids.
We are not into vitamin C or oral products, but ask your friends what works for them. Staying healthy is important when you spend money on a trip.
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